PathJam: a new service for integrating biological pathway information
Full article [PDF] (898,31 kB)
doi:10.2390/biecoll-jib-2010-147
August 19, 2010
October 13, 2010
October 28, 2010
PubMed ID 20980714
Daniel Glez-Peña, Miguel Reboiro-Jato, Rubén Domínguez, Gonzalo Gómez-López, David G Pisano and Florentino Fdez-Riverola
Correspondence should be addressed to:
Florentino Fdez-Riverola
Escuela Superior de Ingeniería Informática University of Vigo, Edificio Politécnico, Campus Universitario As Lagoas s/n, 32004 Ourense, Spain
se.ogivu@nullalorevir
Abstract
Biological pathways are crucial to much of the scientific research today including the study of specific biological processes related with human diseases. PathJam is a new comprehensive and freely accessible web-server application integrating scattered human pathway annotation from several public sources. The tool has been designed for both (i) being intuitive for wet-lab users providing statistical enrichment analysis of pathway annotations and (ii) giving support to the development of new integrative pathway applications. PathJam’s unique features and advantages include interactive graphs linking pathways and genes of interest, downloadable results in fully compatible formats, GSEA compatible output files and a standardized RESTful API.