2.5D Visualisation of Overlapping Biological Networks

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doi doi:10.2390/biecoll-jib-2008-90
submission August 11, 2008
published November 10, 2008
NCBI PubMed PubMed ID 20134057

David CY Fung, Seok-Hee Hong, Dirk Koschützki, Falk Schreiber and Kai Xu

Correspondence should be addressed to:
Falk Schreiber
IPK Gatersleben, Corrensstr. 3, 06466 Gatersleben, Germany
ed.nebelsretag-kpi@nullebierhcs


Abstract

Biological data is often structured in the form of complex interconnected networks such as protein interaction and metabolic networks. In this paper, we investigate a new problem of visualising such overlapping biological networks. Two networks overlap if they share some nodes and edges. We present an approach for constructing visualisations of two overlapping networks, based on a restricted three dimensional representation. More specifically, we use three parallel two dimensional planes placed in three dimensions to represent overlapping networks: one for each network (the top and the bottom planes) and one for the overlapping part (in the middle plane). Our method aims to achieve both drawing aesthetics (or conventions) for each individual network, and highlighting the intersection part by them. Using three biological datasets, we evaluate our visualisation design with the aim to test whether overlapping networks can support the visual analysis of heterogeneous and yet interconnected networks.

Reference

David CY Fung, Seok-Hee Hong, Dirk Koschützki, Falk Schreiber and Kai Xu. 2.5D Visualisation of Overlapping Biological Networks. Journal of Integrative Bioinformatics, 5(1):90, 2008. Online Journal: http://journal.imbio.de/index.php?paper_id=90
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